Matrigel vs geltrex

Hi, is it possible to replace matrigel with geltrex?

Hi Tiam,

This is possible. In fact, some in our lab are doing this right now due to inconsistencies in matrigel lots and production issues.

I would recommend an, “adjustment period” of a couple passages before performing experiments and/or differentiations. It would also be a good idea to verify pluripotency via IF or Flow (I personally like the BD sciences mouse/human pluripotency kit).